Hepatitis A+B Combined Vaccine

What are Hepatitis A and Hepatitis B?

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Hepatitis A and Hepatitis B are two distinct viral infections that affect the liver.

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• Hepatitis A: Transmitted via the faecal-oral route through contaminated food, water, or poor sanitation. It causes severe flu-like illness, abdominal pain, and jaundice.

   

• Hepatitis B: Transmitted through contact with infected blood and bodily fluids, including unprotected sexual contact, unsterilised medical or dental procedures, tattooing/piercing, or accidental needle-stick injuries. Chronic infection can lead to liver cirrhosis, liver failure, and liver cancer.

 

At Livewell Clinic Pharmacy, we offer the private Combined Hepatitis A and B Vaccination Service (Twinrix Adult®) at our Soho, London clinic to provide convenient dual-protection in a single course.

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Why Choose the Combined Hepatitis A & B Vaccine?

 

Rather than receiving separate vaccination courses, the combined jab streamlines your immunisation against both viruses:

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• Dual Protection: Immunises against both Hepatitis A and Hepatitis B simultaneously.

   

• Fewer Injections: Consolidates two separate vaccine courses into one convenient schedule.

   

• Long-Term Immunity: Provides protection for up to 25 years against Hepatitis A and around 5 years (or longer) for Hepatitis B once the full course is completed.

• Essential for High-Risk Travel & Work: Ideal for travellers visiting endemic regions, long-term expatriates, healthcare workers, aid personnel, and individuals with occupational or lifestyle exposure risks.

Dosing Schedule & Course Options

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The combined vaccine course can be administered on a standard or rapid schedule depending on your travel departure date and risk factors:

Trinrix®

1. Standard Schedule (Recommended)

• Dose 1: Day 0

• Dose 2: 1 month after Dose 1

• Dose 3: 6 months after Dose 1 (Provides optimal, long-lasting immunity for planned travel or routine risk)

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2. Accelerated / Rapid Travel Schedule (For Imminent Travel)

• Dose 1: Day 0

• Dose 2: Day 7 (7 days after Dose 1)

• Dose 3: Day 21 (21 days after Dose 1)

• Booster Dose: 12 months after Dose 1 (Suitable for last-minute travellers leaving within a month; the 12-month booster is essential to lock in long-term protection).

 

Ambirix®

• Dose 1: Day 0

• Dose 2: 6-12 months after Dose 1

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​​​Frequently Asked Questions (FAQs)

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Who should consider the combined Hepatitis A & B vaccine?

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The combined vaccine is strongly advised for:

• Travellers visiting countries across Africa, Asia, Central/South America, Eastern Europe, or the Middle East where both viruses are present.

   

• Backpackers, independent travellers, long-term tourists, or those visiting friends and relatives (VFR travel).

   

• Healthcare, dental, laboratory, or emergency response workers.

   

• Humanitarian aid workers or volunteers.

   

• Individuals travelling abroad for medical or dental procedures.

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How far in advance of travel should I book?

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Ideally, you should start your standard course at least 5 weeks before travelling to receive your first two doses. If travelling at short notice, the accelerated schedule allows you to receive 3 doses over 21 days before departure.

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Who should NOT receive the vaccine?

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You should avoid or postpone the combined vaccine if you:

• Have had a severe allergic reaction (anaphylaxis) to a previous dose of Hepatitis A, Hepatitis B, or combined Hepatitis A & B vaccine, or any of their ingredients.

   

• Are currently unwell with an acute severe febrile illness on the day of your appointment.

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What are the common side effects?

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The vaccine is very safe and well tolerated. Mild, temporary side effects usually clear within 1 to 2 days:

 

• Soreness, redness, or mild swelling at the injection site

   

• Mild headache, tiredness, or malaise

   

• Mild digestive upset or low-grade fever

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Can I get this vaccine alongside other travel jabs?

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Yes. Twinrix Adult® can safely be administered at the same visit alongside other routine travel vaccines, such as Yellow Fever, Typhoid, Rabies, or Tetanus using separate injection sites.

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Book Your Hepatitis A+B Combined Vaccination Today

 

Protect your health at home and abroad in three simple steps:

1. Book Online: Select a convenient appointment slot through our online portal.

2. Clinical Assessment: Meet with our pharmacist at our Central London clinic to review your risk factors and select the right dosing schedule.​

3. Vaccination: Receive your jab safely in a private clinical consultation room.